B cells typically help dispel foreign pathogens in

Cabaletta founders Aimee Payne and Michael Milone have modified CAR technology the popular chimeric antigen receptor method that’s enabled the development of successful cell therapies to selectively target and eliminate auto immune disease causing B cells. B cells typically help dispel foreign pathogens in the body, but they can worsen the course of disease in patients with autoimmune disorders. Chimeric autoantibody receptors (CAAR), the company’s modification to currently approved CAR products, are precise and don’t kill all B cells in a patient’s body..

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